Micky van de Ven Double Ends Everton's Unbeaten Streak at Brand New Home Ground
The Dutch defender emerged as the initial defender to net twice in a Premier League match for Tottenham since Jan Vertonghen in March 2013.
Match summary
Micky Van de Ven heads into the net two times in first half
Everton's Jake O'Brien has equalizer disallowed after VAR review
Pape Matar Sarr nets final goal in dying moments
This loss is Everton's first at Hill Dickinson Stadium
Micky van de Ven scored twice as Spurs prolonged their unbeaten run on the road in the Premier League and delivered the Toffees their first defeat at Hill Dickinson Stadium.
Everton were undefeated in their five previous fixtures at their new ground at the dockside location, having departed Goodison Park behind after 133 years at the end of last season.
But Spurs captain Van de Ven struck twice from corners in the first half to put their strong form at risk, and they were failed to turn it around before the midfielder - assisted by ex-Everton forward Richarlison - nodded in a third to put the game to bed.
The Everton defender thought he had levelled the scores a short while after the defender's opener, glancing a powerful header past the Spurs keeper from an Everton corner.
Beto, in the meantime, missed a number of chances, while Vicario made a series of fine stops to ensure the London club went five away games without defeat in the Premier League.
But the VAR stepped in, instructing the match official to review the score on the pitchside monitor and the referee decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Spurs keeper.
The win moves Thomas Frank's team up to third in the division, a handful of points off local foes and leaders the Gunners.
Everton remain 14th and are half a dozen points clear of the relegation zone.
Tottenham analysis: The defender excels in role at each end of pitch
Following a uninspiring midweek performance in the European competition against the French side, where they mustered a mere two shots on target, Frank opted for Randal Kolo Muani in attack instead of ex-Everton forward the Brazilian.
The new arrival was unable to influence the game before being substituted for Richarlison after an hour on the pitch, but it emerged he proved unnecessary in the final outcome.
Centre-back Van de Ven transformed into an attacking force to be feared.
Spurs' first goal came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball back across the six-yard box for an unmarked Van de Ven to head home.
And Ven de Ven - filling in as captain in Cristian Romero's unavailability - notched his next goal in added time as he rose above the England keeper to head home.
The Dutchman was just as impressive in defensive duties, partnering well with Kevin Danso as the pair dealt superbly with the 34 crosses sent their way by Everton.
Toffees breakdown: Toffees missing finishing touch
Everton's new home had been a fortress, but it seems the freshness may have worn off somewhat and fans headed to the gates after Sarr's final goal for Spurs.
The break in Everton's winning streak at home won't be a massive worry for the manager, but their striker situation will be.
Beto and the other striker - the Toffees' two recognised centre-forwards - had netted just one league goal combined before the weekend's match.
And they were unable to contribute to that poor tally on a wet and gloomy night on in Liverpool.
Beto's performance was epitomized when he chose to overhead kick a clear chance from close range, even with having room and opportunity to reposition for a simpler attempt that would have tested Vicario.
Barry, too, failed to influence the game after coming on for the starter in the second half.
It wasn't for a lack of chance. Most of Everton's offensive moves came through Grealish and Ndiaye, who relentlessly delivered threatening crosses into the Spurs penalty area.
Upcoming fixtures for both teams?
The Toffees: Moyes' men travel to the Stadium of Light in the Premier League on Monday, 3 November at 8 PM.
Tottenham: Spurs go to St James' Park on Wednesday, 29 October for their fourth-round Carabao Cup tie against Newcastle.